Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)
Last verified by NonDilute: 2026-04-29. Official notice and agency instructions control.
If you hold an active NIH grant and an emergency NOSI matches your research, rapid supplemental funding is available to redirect your work toward the crisis.
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What this is
This is a rapid-response funding mechanism for researchers with existing NIH grants who need to pivot or expand their work in response to emergencies—such as declared disasters under the Stafford Act or HHS public health emergencies. You cannot apply directly to this NOFO; instead, you must wait for NIH institutes to publish Emergency NOSIs on specific topics, then submit your supplement application addressing that emergency research need. Award amounts are not specified in this announcement.
Who can apply
You must already be a PI or co-PI on an active NIH award. Eligible organizations include universities, nonprofits (501(c)(3) and non-501(c)(3)), small businesses, for-profit companies, tribal governments, state/local governments, and others. You can only apply in response to a specific Emergency NOSI published by an NIH component; unsolicited applications are not accepted.
Eligible applicant types
- Public and State controlled institutions of higher education
- Special district governments
- County governments
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Native American tribal organizations (other than Federally recognized tribal governments)
- Small businesses
- Private institutions of higher education
- City or township governments
- Public housing authorities/Indian housing authorities
- Independent school districts
- For profit organizations other than small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Native American tribal governments (Federally recognized)
- State governments
Full description — from the agency
The National Institutes of Health (NIH) hereby notify the applicant community that funds may be available for applications based on a presidentially declared disaster under the Stafford Act, a public health emergency declared by the Secretary, HHS, or other local, regional or national disaster. Applications in response to Emergency Notices of Special Interest (NOSIs) will be routed directly to the NIH awarding component signed on to the Emergency NOSI. Only applications submitted in response to an Emergency NOSI published by an IC will be allowed to apply to this NOFO.
Topics: emergency supplement funding · NIH disaster response · public health emergency research · research grant revision · emergency NOSI
Public-source funding discovery only. This summary is generated from public agency data and may be incomplete or stale. NonDilute is not affiliated with, endorsed by, or acting on behalf of any government agency. Official notices and agency instructions control. NonDilute does not determine eligibility, provide grant-writing advice, or guarantee funding.