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Startup R&D opportunities

68 currently open federal R&D records filtered for U.S. technical founders: SBIR/STTR, small-business eligibility, commercialization language, R&D/prototype language, and core tech-sector fit.

Last verified by NonDilute: 2026-04-29. Records that look nonprofit-only, embassy-only, AmeriCorps/service-program, local/community, or academic-only are kept out of this founder-facing surface.

National Energy Technology Laboratory
21d left

Infrastructure Investment and Jobs Act (IIJA) — Speed to Power through Accelerated Reconductoring and other Key Advanced Transmission Technology Upgrades (SPARK)

SPARK funds infrastructure upgrades and advanced transmission technologies to increase U.S. electric grid capacity, reliability, and resilience. Projects must combine physical infr…

Idaho Field Office
41d left

Fiscal Year 2026 Consolidated Innovative Nuclear Research

U.S. Department of Energy funding to advance nuclear energy science and technology, including reactor operation, advanced reactor deployment, nuclear fuel cycles, and maintaining U…

DOC NOAA - ERA Production
77d left

FY 2026 Ocean Technology Transition Program

NOAA is funding the transition of ocean and coastal observing technologies from research into operational use, supporting sensors, data management, and decision-support products th…

Idaho Field Office
Rolling

RFI - DOE R

The DOE Office of Nuclear Energy is conducting a Request for Information (RFI) to gather ideas and feedback on future research priorities and work scopes for its nuclear energy res…

Headquarters
Rolling

Sequestration Information

This is a notice about federal budget sequestration, not a funding opportunity. It provides information on how automatic spending cuts may affect federal programs and funding.

Golden Field Office
86d left

Unleashing Tribal Energy Development

The U.S. Department of Energy is offering $50 million to Native American tribal governments and organizations to develop energy projects that advance tribal sovereignty and meet co…

Food and Drug Administration
Rolling

Improving Predictability of Food-Drug and Drug-Drug Interaction Risks by Utilizing In Vitro Simulated Gastrointestinal Dissolution Model for High-Risk Oral Drug Products (U01) Clinical Trial Optional

This FDA funding opportunity seeks research to improve prediction of food-drug and drug-drug interactions using in vitro gastrointestinal dissolution models for high-risk oral medi…

National Institute of Food and Agriculture
58d left

Open Data Framework

This funding builds secure data repositories and cooperatives where farmers, universities, and nonprofits can store and share agricultural data to drive innovation and profitabilit…

National Institute of Food and Agriculture
61d left

Methyl Bromide Transition Program

This grant funds research and development of practical alternatives to methyl bromide for pest management in agriculture, post-harvest systems, and transport. Awards up to $500,000…

National Institute of Food and Agriculture
55d left

Rural Health and Safety Education Competitive Grants Program

This grant funds projects that improve health and safety education in rural communities through food, agriculture, natural resources, and human sciences initiatives. Awards are fix…

Food and Drug Administration
Rolling

Animal Food Regulatory Program Alliance

FDA funding to support regulatory alignment and collaboration on animal food safety standards and compliance programs. This appears to be a cooperative agreement or alliance-buildi…

Food and Drug Administration
Rolling

Utilizing Real-World Data and Algorithmic Analyses to Assess Post-Market Clinical Outcomes in Patients Switching Amongst Therapeutically Equivalent Complex Generic Drug Products and Reference Listed Drugs (U01) Clinical Trial Not Allowed

The FDA is funding research to assess real-world clinical outcomes when patients switch between generic and brand-name complex drug products. This U01 grant supports algorithmic an…

Food and Drug Administration
859d left

Vet-LIRN Capacity-Building Project and Equipment Grants (U18)

FDA funding for veterinary diagnostic laboratories to develop, validate, and deploy testing methods for animal food safety, antimicrobial resistance, and emerging diseases. Grants …

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