124 currently open federal R&D records filtered for U.S. technical founders: SBIR/STTR, small-business eligibility, commercialization language, R&D/prototype language, and core tech-sector fit.
Last verified by NonDilute: 2026-06-08. Records that look nonprofit-only, embassy-only, AmeriCorps/service-program, local/community, or academic-only are kept out of this founder-facing surface.
PACER funds pioneering aerospace research and engineering capabilities through the Air Force Research Lab. This is a broad, long-term research program open to any entity type.
This Air Force Research Lab program funds development of geospatial intelligence processing and exploitation technologies. It supports research and prototype development in image a…
NAVAIR is soliciting white papers for R&D projects that advance Naval Air Warfare Center Aircraft Division operations. This is a broad, open call for innovative solutions in aircra…
This Air Force Research Lab opportunity funds automated processes for knowledge discovery and information retrieval, likely applied to defense and intelligence applications. The fi…
This is a general outreach and invitation for research proposals from the U.S. Army Medical Research Acquisition Activity (USAMRAA), likely related to military medical or biologica…
The U.S. Army Research Institute for the Behavioral and Social Sciences (ARI) funds basic, applied, and advanced research in behavioral and social sciences to improve Army readines…
STARBASE Cherry Point is a Department of Navy/NAVAIR funding opportunity, likely supporting science, technology, research, or engineering activities at or near the Cherry Point Nav…
The U.S. Army is soliciting proposals for fundamental artificial intelligence research through a Broad Agency Announcement. This is an open call for innovative AI/ML work aligned w…
NSWC Crane seeks innovative research and technology demonstrators advancing naval warfare capabilities across electronic warfare, sensors, strategic systems, and related defense te…
The Air Force Research Lab is funding foundational research into trusted systems—likely covering security, verification, and reliability in defense-critical computing. This is a lo…
The Air Force Research Laboratory seeks innovative solutions across human performance, medical, and operational technology domains through a multi-track funding mechanism spanning …
NSF supports foundational research on robotic systems that integrate computational intelligence, sensing, and physical embodiment. Projects must demonstrate new or significantly en…
The NSF Expeditions in Computing program funds ambitious, transformative research projects in computer and information science engineering at up to $15 million over seven years. It…
STARBASE Wright Patt is an Air Force Research Lab funding opportunity, likely focused on science, technology, engineering, and mathematics (STEM) education or research initiatives …
NSF funding for fundamental research advancing design science and systems engineering through rigorous inquiry into how engineered artifacts are created. Supports multidisciplinary…
The Partnership Intermediary Agreement (PIA) is a Department of Defense mechanism that enables qualified intermediaries to facilitate technology partnerships and commercialization …
The CHIPS Incentives Program provides federal funding for construction, expansion, or modernization of commercial semiconductor materials and manufacturing equipment facilities to …
This is an SBIR Phase II grant from the Administration for Community Living (ACL) for small businesses developing innovative solutions in aging, disability, and community living se…
NSF funding for fundamental research on bidirectional human-machine interaction in physics-based environments, covering robotics, smart systems, and virtual/physical collaboration.…
NSF funding for fundamental research in mechanics of materials and structures, including deformation, fracture, fatigue, and computational methods. Supports experimental, theoretic…
The Air Force Research Laboratory is funding research on human performance, health, and wellbeing across all technical areas through the CHEERS program. Researchers can submit whit…
The Air Force Research Laboratory seeks white papers and technical proposals for human-centered research in enabling, enhancing, restoring, and sustaining capabilities under the CH…
DSCU funds unclassified research on security cooperation and irregular warfare to build knowledge applicable to DoD policy and practice. Grants range from $2,500 to $800,000 and re…
NIST awards grants to develop and expand research in measurement science, standards, nanotechnology, AI, advanced manufacturing, and related fields that strengthen U.S. innovation …
NOAA is funding the development and testing of technologies to prevent, control, or mitigate harmful algal blooms in marine and coastal environments. Awards up to $1M/year are avai…
DOE funding to advance bench-scale innovations in critical minerals and materials processing—rare earths, lithium extraction, and semiconductor materials—from lab to pilot producti…
ARPA-E's SCALEUP READY program funds transformative energy technology research and development with $5–20 million awards to advance early-stage innovations toward commercial viabil…
NSF funding to support U.S.-based research teams leading international multilateral partnerships (with at least 2 non-U.S. countries) that tackle global research challenges requiri…
Federal funding for research centers developing AI-driven assistive and rehabilitation technologies to improve outcomes for people with disabilities. Administered by the Administra…
NSF's Computational and Data-Enabled Science and Engineering (CDS&E) meta-program funds research that uses novel computational and data-science approaches to solve major science an…
U.S. Department of Energy funding to advance nuclear energy science and technology, including reactor operation, advanced reactor deployment, nuclear fuel cycles, and maintaining U…
NOAA is funding the transition of ocean and coastal observing technologies from research into operational use, supporting sensors, data management, and decision-support products th…
NOAA's Climate Program Office is funding climate research addressing societal challenges like water resources, coastal resilience, marine ecosystems, and extreme weather. The FY 20…
This grant program provides cost-sharing funding to support the licensing and regulatory approval of advanced nuclear energy technologies. Applicants can receive between $5,000 and…
NSF is funding collaborative research teams to develop the mathematical and theoretical foundations of AI systems, focusing on understanding their capabilities, limitations, and de…
The DOE Office of Nuclear Energy is conducting a Request for Information (RFI) to gather ideas and feedback on future research priorities and work scopes for its nuclear energy res…
NSF funding to build collaborative research data infrastructure ecosystems that improve public access, discoverability, and reusability of federally-funded research data across sci…
NSF's Molecular and Cellular Biosciences program funds fundamental research into how living systems work at the molecular and cellular level, emphasizing mechanistic understanding …
This federal program distributes up to $150 million to reduce truck idling and emissions at port facilities, with emphasis on electrification infrastructure. Eligible entities can …
This is a notice about federal budget sequestration, not a funding opportunity. It provides information on how automatic spending cuts may affect federal programs and funding.
The U.S. Department of Energy is offering $50 million to Native American tribal governments and organizations to develop energy projects that advance tribal sovereignty and meet co…
This NSF/DOE joint program funds research that ensures scientific computing software and systems are mathematically correct and free of numerical, logical, and hardware errors. It …
NOAA is funding fish habitat restoration projects in the Great Lakes region to support native fish populations and address toxic contamination. Awards range from $250,000 to $30 mi…
NSF funds fundamental research on analytical methods—modeling, optimization, simulation, data science—that improve operations in complex decision-making environments across commerc…
NOAA's Office of Education seeks applications for special projects and programs aligned with NOAA's strategic plan and mission goals. This is a broad, open call for discretionary f…
NOAA is accepting applications for special projects and programs aligned with its strategic plan and mission goals across multiple Line Offices. This is a broad, open funding mecha…
NOAA is seeking applications for special projects and programs aligned with the National Weather Service strategic plan and mission goals through a broad agency announcement. This …
NSF and Germany's DFG are jointly funding collaborative research between US and German researchers in chemistry and chemical process/transport systems. Applicants submit one propos…
This NCI award supports talented postdoctoral researchers with research or clinical doctorates as they transition from mentored positions to independent, tenure-track faculty roles…
NIH funding opportunity for small businesses developing medical technology and digital health innovations. The program aims to translate research into commercially viable products …
NSF funding for research on Earth's climate, environments, and life evolution from the Archean Eon through the Holocene epoch. Research spans molecular to global scales and support…
This FDA funding opportunity seeks research to improve prediction of food-drug and drug-drug interactions using in vitro gastrointestinal dissolution models for high-risk oral medi…
NIH funding opportunity for developing therapeutic treatments using extracellular vesicles (cell-derived nanoparticles) for regenerative medicine applications. This initiative supp…
This NIH SBIR Phase IIB Bridge award funds small businesses developing cancer-relevant technologies toward commercialization, with an optional clinical trial component.
The Department of Defense seeks management and conservation efforts for western bumble bee populations at Joint Base Elmendorf-Richardson in Alaska. This is a species management an…
NOAA is funding the development of innovative, cost-effective technologies to detect harmful algal bloom toxins in seafood. Awards of $100k–$250k annually (up to $750k total) will …
NIDA is funding research to identify genetic and genomic variants underlying substance use disorders (SUD), addictive behaviors, and related comorbidities in animal models. The pro…
NIH seeks research partnerships between academic institutions and industry to develop and commercialize bioengineering tools and technologies that address unmet biomedical needs. A…
This NIH grant funds development of digital health technology (DHT)-derived biomarkers and clinical outcomes for use as endpoints in remote monitoring clinical trials. Applicants m…
This funding builds secure data repositories and cooperatives where farmers, universities, and nonprofits can store and share agricultural data to drive innovation and profitabilit…
NIFA is funding research to improve alfalfa seed and forage production systems, including breeding, management practices, harvest technology, and novel uses. Award range is $150K–$…
USDA's National Institute of Food and Agriculture is funding applied research to develop science-based solutions that make U.S. aquaculture more profitable and competitive. Project…
The FDA is funding novel approaches to accelerate therapeutic development for ultra-rare cancers (≤300–400 annual U.S. cases). Support covers infrastructure, clinical endpoints, re…
USDA funding to develop and scale alternative crops (oilseeds, grains, legumes, pseudocereals) for food, animal feed, industrial chemicals, and biofuels. Projects must demonstrate …
This USDA grant funds research to understand the genetics and traits of agriculturally important crops and animals, with the goal of improving breeding, disease resistance, and pro…
This grant funds research and development of practical alternatives to methyl bromide for pest management in agriculture, post-harvest systems, and transport. Awards up to $500,000…
NIFA funding for integrated pest management (IPM) research, extension, and education to control insects, weeds, pathogens, and invasive species in agriculture. Supports projects th…
NRCS is funding on-farm conservation innovation trials where eligible organizations recruit farmers and provide technical assistance and payments to test new conservation practices…
NIH funding to clinically validate cancer biomarker assays that have already been analytically validated. Support is provided for validation studies using clinical specimens over u…
This NIH grant supports feasibility clinical trials testing mind-body interventions (complementary and integrative health approaches) for high-priority conditions identified by NCC…
The NIH R25 Summer Research Education Experience Program funds educational activities that teach high school students, undergraduates, or science teachers about biomedical, behavio…
This NIH funding supports research to understand why people respond differently to probiotic therapies and to identify the biological patterns that predict who benefits. It uses a …
NIH funding to support mechanistic research identifying which patient subgroups respond best to probiotic therapies by studying host biology factors like microbiome, genetics, diet…
NIH funding to conduct clinical trials and observational studies on women, children, pregnant/lactating women, and persons with disabilities using existing NICHD research network i…
NIH funding to develop and clinically test therapeutic or diagnostic devices for nervous system and neuromuscular disorders, from prototype through FDA regulatory milestones.
The National Cancer Institute (NCI) offers the MERIT (Method to Extend Research in Time) Award to provide early-stage investigators with up to 7 years of extended grant support to …
The FDA's OMHHE Health Equity Innovation Award funds projects that advance health equity and reduce disparities in medical device or pharmaceutical access and outcomes. Clinical tr…
NIH funding for computational research modeling how genetic variation affects biological function, excluding clinical trial work. Awards support foundational genomics research usin…
NIH funding to characterize how individual genetic variants affect genome function and phenotype through systematic research. Clinical trials are explicitly not permitted under thi…
NIH funding for technology projects within the Cellular Senescence Network (SenNet) initiative, excluding clinical trial applications. This supports research and tool development r…
NIH funding to develop non-addictive small molecule and biologic pain therapeutics, with optional clinical trial support through the UG3/UH3 mechanism.
This NIH/FDA grant funds development of physiologically-based pharmacokinetic (PBPK) modeling and in vitro-in vivo correlation (IVIVC) methods for long-acting injectable suspension…
The NIH K25 award provides funding and protected time for scientists with quantitative backgrounds (math, statistics, CS, physics, etc.) to transition their expertise into health-f…
The FDA is funding research to identify and evaluate approaches for addressing nitrosamine impurities found in pharmaceutical drugs. This is a U01 cooperative agreement focused on …
USDA and Department of Interior joint program funding research on fire science and management to improve wildfire prevention and response. Supports applied research projects addres…
This grant funds projects that improve health and safety education in rural communities through food, agriculture, natural resources, and human sciences initiatives. Awards are fix…
This is a change-of-ownership mechanism for organizations already holding specific NIH grants to transfer those awards to a new recipient organization. It is not a new funding oppo…
The FDA is funding research to assess real-world clinical outcomes when patients switch between generic and brand-name complex drug products. This U01 grant supports algorithmic an…
FDA funding to support health equity innovations that are NOT clinical trials. Likely targets research, products, or services that reduce healthcare disparities.
FDA funding to support regulatory alignment and collaboration on animal food safety standards and compliance programs. This appears to be a cooperative agreement or alliance-buildi…
FDA funding to support outsourcing facilities that produce drugs in short supply while implementing fraud prevention measures. The goal is to reduce barriers and increase capacity …
NIH funding for research on interventions to improve dementia care and support for caregivers, supporting Stages II through V of research development. This opportunity targets inve…
USDA APHIS is distributing $12.05M in cooperative agreement funding to control and prevent Chronic Wasting Disease (CWD) in both wild and farmed cervid populations. Applicants can …
This USDA program distributes micro-grants to state agricultural agencies to fund small-scale food production (gardening, livestock) in food-insecure communities. Projects should p…
CIDR provides NIH-funded high-throughput genomic sequencing and genotyping services plus statistical genetics support to help researchers identify disease-causing genes and enhance…
The NIH Blueprint Neurotherapeutics Network funds small molecule drug discovery and development projects targeting nervous system disorders, from hit optimization through Phase I c…
This is a broad agency announcement from NOAA's National Marine Fisheries Service seeking applications for research, projects, and programs aligned with NOAA Fisheries' strategic g…
NIH grant to fund early-stage drug discovery research for pain therapeutics that are safe, effective, and non-addictive. Projects must focus on assay development, screening, and in…
NIH is offering emergency supplemental funding to expand or revise existing NIH-funded research projects in response to declared disasters or public health emergencies. Applicants …
NIH funding for discovery and development of biologic-based therapeutics (proteins, antibodies, gene therapies, cell therapies) for nervous system disorders, from lead optimization…
NIH funding to research how biospecimen collection, processing, and storage conditions affect clinical biomarker detection and assay development. The goal is standardizing biopsy h…
This NIH grant funds cancer research using biospecimens and data from the PLCO Screening Trial, supporting studies on cancer etiology and early detection biomarkers. Applicants mus…
NIH funding to support planning and feasibility studies for clinical trials in cancer prevention, screening, early detection, and survivorship care. Designed to fill knowledge gaps…
This NIH grant funds planning and feasibility studies for cancer prevention and control clinical trials to resolve design uncertainties before full trial launch. It supports prepar…
FDA funding for veterinary diagnostic laboratories to develop, validate, and deploy testing methods for animal food safety, antimicrobial resistance, and emerging diseases. Grants …
FDA funding to develop novel therapeutic approaches for ultra-rare cancers. This program supports innovative treatment strategies for cancer subtypes with very limited patient popu…
This FDA funding opportunity supports research to identify drug and formulation factors that cause alcohol dose dumping in modified-release oral medications. The goal is to underst…
This NIH/FDA grant funds research on measuring how topical drugs penetrate and distribute through skin using pharmacokinetic tomography, a novel imaging technique. Applicants must …
This FDA funding supports research into evaluating and treating heart damage caused by cancer drugs. It focuses on applied regulatory science to address cardiotoxicity, a serious s…
USDA grant program funding renewable energy systems and energy efficiency improvements for small businesses and rural organizations, with awards ranging from $1,500 to $500,000.
USDA grants for rural businesses and organizations to install renewable energy systems and improve energy efficiency. Funding ranges from $1,500 to $500,000.
This Department of the Interior grant funds projects that protect coral reefs and natural resources in U.S. insular areas, with emphasis on food security, shoreline protection, eco…
The EPA is funding organizations to collect and analyze phytoplankton and chlorophyll-a samples across the Great Lakes as part of a water quality monitoring network required by the…
FDA funding to support collaborations that advance drug development processes and strengthen regulatory science capabilities. The opportunity aims to bridge gaps between industry, …
GREGoRi Innovation Projects is an NIH funding opportunity for research projects, with optional clinical trial components. Limited details are publicly available on this funding mec…
NSF/NIFA joint program funding research on how plants interact with viruses, bacteria, fungi, pests, and beneficial microorganisms. Supports both fundamental discovery and applied …
This NIH grant funds multi-project research centers (P50 SPOREs) focused on translational cancer research for organ-specific or biologically-related cancer groups. Awards support s…
The NIH K01 award provides 3–5 years of mentored career development support for early-stage researchers in biomedical, behavioral, or clinical sciences who are not leading their ow…
The NIH Pathway to Independence Award (K99/R00) helps postdoctoral researchers with research or clinical doctorates transition to independent, tenure-track faculty positions with u…
The NIH K24 award provides 3–5 years of funding to mid-career health professionals to conduct patient-oriented research and mentor junior clinical researchers. This is for establis…
The NIH Pathway to Independence Award (K99/R00) helps talented postdoctoral researchers with research or clinical doctorates transition from mentored positions to independent, tenu…
The NIH K08 award provides mentored research career development funding for individuals with clinical doctoral degrees (MDs, DOs, DMDs, etc.) to conduct intensive biomedical or beh…
The NIH K23 award supports early-career clinicians (MDs, DOs, DMDs, DPMs, etc.) who commit to patient-oriented research. It funds salary, mentorship, and research costs for individ…
This NIH funding opportunity supports the establishment or operation of a genome sequencing center dedicated to the Gabriella Miller Kids First Pediatric Research Program, excludin…