Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)
Last verified by NonDilute: 2026-04-29. Official notice and agency instructions control.
If you have preliminary evidence linking bariatric surgery outcomes to cancer pathways, NCI will fund 4+ years of mechanism research with up to $500k per year.
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What this is
NCI seeks investigator-initiated research proposals examining the mechanistic pathways by which bariatric surgery influences cancer risk, moving beyond short-term outcomes like weight loss and diabetes remission. This R01-level grant (up to $500k) is open to a broad range of eligible entities including universities, nonprofits, small businesses, and government organizations. Applicants should have established research capacity and preliminary data or compelling rationale for studying bariatric surgery's long-term impact on oncological outcomes.
Who can apply
Extremely broad eligibility including universities, nonprofits with or without 501(c)(3) status, small businesses, state and local governments, tribal organizations, and for-profit organizations. Solo researchers must be affiliated with an eligible institution. No geographic restriction mentioned.
Eligible applicant types
- For profit organizations other than small businesses
- Special district governments
- Independent school districts
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- City or township governments
- Public and State controlled institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Small businesses
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- County governments
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally recognized tribal governments)
- Private institutions of higher education
- State governments
- Public housing authorities/Indian housing authorities
Full description — from the agency
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter-term outcomes such as weight loss and diabetes.
Topics: bariatric surgery cancer risk · cancer mechanisms research · obesity and oncology · investigator-initiated R01 · NIH clinical research · translational cancer biology
Public-source funding discovery only. This summary is generated from public agency data and may be incomplete or stale. NonDilute is not affiliated with, endorsed by, or acting on behalf of any government agency. Official notices and agency instructions control. NonDilute does not determine eligibility, provide grant-writing advice, or guarantee funding.