Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)
Last verified by NonDilute: 2026-04-29. Official notice and agency instructions control.
If you're a researcher with lab capacity investigating the biological roots of cancer disparities, this multi-year R01 provides sustained funding with minimal clinical trial restrictions.
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What this is
This R01 grant from the National Cancer Institute (CFDA 93.393) funds fundamental research into biological and genetic mechanisms underlying cancer health disparities—not clinical trials. Eligible projects include mechanistic studies of cancer biology, development of new research models and tools (biospecimens, patient-derived models), and secondary data analyses. The program explicitly seeks to grow a nationwide cohort of basic researchers with deep expertise in cancer disparities, expanding the resource base for future research.
Who can apply
Extremely broad: universities (public and private), nonprofits with 501(c)(3) status, small businesses, state/local governments, tribal governments, and for-profit organizations. Solo researchers must be affiliated with an eligible institution. No geographic restrictions.
Eligible applicant types
- Special district governments
- County governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- City or township governments
- Small businesses
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Native American tribal governments (Federally recognized)
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- State governments
- For profit organizations other than small businesses
- Public housing authorities/Indian housing authorities
- Independent school districts
- Public and State controlled institutions of higher education
Full description — from the agency
This Notice of Funding Opportunity (NOFO) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants will support innovative studies designed to investigate biological/genetic bases of cancer disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and testing of new methodologies and models, and (3) secondary data analyses. This NOFO is also designed to aid and facilitate the growth of a nationwide cohort of scientists with a high level of basic research expertise in cancer health disparities research who can expand available resources and tools, such as biospecimens, patient derived models, and methods that are necessary to conduct basic research in cancer health disparities.
Topics: cancer health disparities · basic research grants · mechanistic biology · cancer genetics · NIH R01 · biospecimen development
Public-source funding discovery only. This summary is generated from public agency data and may be incomplete or stale. NonDilute is not affiliated with, endorsed by, or acting on behalf of any government agency. Official notices and agency instructions control. NonDilute does not determine eligibility, provide grant-writing advice, or guarantee funding.