Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Last verified by NonDilute: 2026-04-29. Official notice and agency instructions control.
If you can unlock cancer insights by combining and re-analyzing existing datasets with novel methods, NIH will fund you up to $350K without requiring new patient enrollment or clinical trials.
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What this is
This R01-equivalent grant supports research teams analyzing and combining existing datasets—clinical records, surveillance databases, genomic repositories, health services data—to advance cancer science. You must use pre-existing data and cannot conduct new clinical trials. The focus is on novel analytical methods, creative dataset integration, or new research questions addressed through existing resources. Awards up to $350K support investigators across nonprofits, small businesses, universities, government, and tribal organizations.
Who can apply
Broad eligibility: nonprofits (with or without 501(c)(3) status), small businesses, for-profit companies, universities (public and private), government agencies, tribal organizations, and school districts. No geographic restriction mentioned. Explicit restriction: no new clinical trials allowed; must use existing data.
Eligible applicant types
- Independent school districts
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- City or township governments
- Public housing authorities/Indian housing authorities
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Special district governments
- Native American tribal organizations (other than Federally recognized tribal governments)
- Small businesses
- County governments
- Native American tribal governments (Federally recognized)
- State governments
- Public and State controlled institutions of higher education
- Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Private institutions of higher education
- For profit organizations other than small businesses
Full description — from the agency
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) along with other participating Institutes encourages submission of applications proposing to conduct secondary data analysis and integration of existing datasets and database resources, with the ultimate aim to elucidate cancer risk and related outcomes (e.g., risk prediction or reduction, survival, or response to treatment, etc.). The goal of this initiative is to address key scientific questions relevant to cancer by supporting the analysis of existing clinical, environmental, surveillance, health services, vital statistics, behavioral, lifestyle, genomic, and molecular profiles data. Applicants are encouraged to leverage and perform innovative analyses of the existing data. Applications may include new research aims that are being addressed with existing data, new or advanced methods of analyses, or novel combinations and integration of datasets that allow the exploration of important scientific questions in cancer research.
Topics: cancer risk analysis · secondary data analysis · dataset integration · genomic epidemiology · biomedical data science · NIH grant · cancer informatics
Public-source funding discovery only. This summary is generated from public agency data and may be incomplete or stale. NonDilute is not affiliated with, endorsed by, or acting on behalf of any government agency. Official notices and agency instructions control. NonDilute does not determine eligibility, provide grant-writing advice, or guarantee funding.