Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed)
Last verified by NonDilute: 2026-06-08. Official notice and agency instructions control.
Pursue NIH funding for mechanistic genomics research if you have unpublished data on how genetic or environmental factors interact to drive phenotypes—but expect rigorous peer review and don't plan a clinical trial.
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What this is
The UM1 mechanism supports research investigating epistatic (variant-variant) and gene-environment interactions in genomic studies. This is hypothesis-driven basic or translational research aimed at understanding biological mechanisms underlying complex traits or diseases. The funding is intended for investigators with strong preliminary data and established research programs; clinical trial projects are explicitly excluded.
Who can apply
Eligible applicants likely include universities, research institutions, and individual researchers with Ph.D. or M.D. credentials. Specific eligibility (organization size, geography, citizenship) is not stated in the source; applicants should verify via NIH Grants.gov or contact the administering IC for CFDA 93.172.
Topics: genomic variants · gene-environment interaction · epistasis · complex disease genetics · NIH genomics research
Public-source funding discovery only. This summary is generated from public agency data and may be incomplete or stale. NonDilute is not affiliated with, endorsed by, or acting on behalf of any government agency. Official notices and agency instructions control. NonDilute does not determine eligibility, provide grant-writing advice, or guarantee funding.